Quiz: Pharmacology

The following drugs should be avoided in peptic ulcer except:

A cortisone B aspirin C phenylbutazone D oestrogen

Metabolic alkalosis is a side effect of_the following antacid:

A aluminium hydroxide B sodium bicarbonate C calcium carbonate.

Which of the following drugs is H2 antagonist?

A cyproheptadine B pheniramine C ranitidine D serotonin

Therapeutic uses of laxatives include the following:

A constipation B orally ingested drug poisoning C before and after surgery of hernia & haemorrhoids D all of the above

Therapeutic uses of laxatives include the following except:

A before surgical operations B food poisoning C before coloscopy & x rays D intestinal colic E hepatic encephalopathy

Gynaecomastia can occur as a side effect of:

A Omeprazole B Cimetidine C Famotidine D Almunium hydroxide E Sucralfate

Ranitidine differs from cimetidine in the following respect:

A It is less potent B It is shorter acting C It does not have anti-androgenic action D It produces more CNS side effects E It isn’t H2 blocker

The most efficacious drug for inhibiting 24 hours gastric acid output is:

A Omeprazole B Cimetidine C Pirenzepine D Misoprostol E Sucralfate

The first choice drug for nonsteroidal anti-inflammatory drug associated gastric ulcer is:

A Omeprazole B Misoprostol C Ranitidine D Sucralfate E Cimitidine

Select the drug which is an inhibitor of gastric mucosal proton pump:

A Carbenoxolone sodium B Sucralfate C Famotidine D Lansoprazole E Pirenzepine

Sucralfate promotes healing of duodenal ulcer by:

A Enhancing gastric mucus and bicarbonate secretion B Coating the ulcer and preventing the action of acid-pepsin on ulcer base C Promoting regeneration of mucosa D Block H2 receptors E Block M1 receptors

Antacids administered concurrently reduce efficacy of the following antipeptic ulcer drug:

A Cimetidine B Colloidal bismuth C Sucralfate D Pirenzepine E Ranitidine

Which of the following antibacterial drugs is used commonly to eradicate intestinal H pylori?

A Cefazolin B Ciprofloxacin C Clarithromycin D Clindamycin E Vancomycin

Choose the correct statement about colloidal bismuth subcitrate:

A It causes prolonged neutralization of gastric acid B It has anti-H.pylori activity C It relieves peptic ulcer pain promptly D It blocks H2 receptors E It blocks both M1 and H2 receptors

The following antiulcer drug does not act by reducing the secretion of or neutralizing gastric acid:

A Famotidine B Sucralfate C Misoprostol D Omeprazole E Pirenzipine

To prevent chemotherapy-induced nausea and vomiting, which of the following should be used?

A Levodopa B Methotrexate C Misoprostol D Ondansetron E Sucralfate

1-The following drugs should be avoided in peptic ulcer except:

A a-cortisone B b-aspirin C c-phenylbutazone D d-oestrogen

2-Metabolic alkalosis is a side effect of_the following antacid:

A a-aluminium hydroxide B b-sodium bicarbonate C c-calcium carbonate. D ..

3-Which of the following drugs is H2 antagonist?

A a-cyproheptadine B b-pheniramine C c-ranitidine D d-serotonin

4-Therapeutic uses of laxatives include the following:

A a-constipation. B b-orally ingested drug poisoning. C c-before and after surgery of hernia & haemorrhoids. D d-all of the above.

5-Therapeutic uses of laxatives include the following except:

A a-before surgical operations B b-food poisoning. C c-before coloscopy & x rays. D d- intestinal colic.

1-Gynaecomastia can occur as a side effect of:

A a) Omeprazole B b) Cimetidine C c) Famotidine D d) Almunium hydroxide

2-Ranitidine differs from cimetidine in the following respect:

A a) It is less potent B b) It is shorter acting C c) It does not have anti-androgenic action D d) It produces more CNS side effects

3-The most efficacious drug for inhibiting 24 hours gastric acid output is:

A a) Omeprazole B b) Cimetidine C c) Pirenzepine D d) Misoprostol

4- The first choice drug for nonsteroidal anti-inflammatory drug associated gastric ulcer is:

A a) Omeprazole B b) Misoprostol C c) Ranitidine D d) Sucralfate

5- Select the drug which is an inhibitor of gastric mucosal proton pump:

A a) Carbenoxolone sodium B b) Sucralfate C c) Famotidine D d) Lansoprazole

6- Sucralfate promotes healing of duodenal ulcer by:

A a) Enhancing gastric mucus and bicarbonate secretion B b) Coating the ulcer and preventing the action of acid-pepsin on ulcer base C c) Promoting regeneration of mucosa D d) Block H2 receptors

7- Antacids administered concurrently reduce efficacy of the following antipeptic ulcer drug:

A a) Cimetidine B b) Colloidal bismuth C c) Sucralfate D d) Pirenzepine

8- Which of the following antibacterial drugs is used commonly to eradicate intestinal H pylori?

A a) Cefazolin B b) Ciprofloxacin C c) Clarithromycin D d) Clindamycin

9- Choose the correct statement about colloidal bismuth subcitrate:

A a) It causes prolonged neutralization of gastric acid B b) It has anti-H.pylori activity C c) It relieves peptic ulcer pain promptly D d) It blocks H2 receptors

10-The following antiulcer drug does not act by reducing the secretion of or neutralizing gastric acid

A a) Famotidine B b) Sucralfate C c) Misoprostol D d) Omeprazole

1-To prevent chemotherapy-induced nausea and vomiting, which of the following should be used?

A a) Levodopa B b) Methotrexate C c) Misoprostol D d) Ondansetron

2- Which prokinetic drug produce extrapyramidal side effects

A a) Metoclopramide B b) Cimitidine C c) Domperidone D d) Ondansetron

3- Granisetron is a:

A a) Second generation antihistaminic B b) Drug for peptic ulcer C c) Antiemetic for cancer chemotherapy D d) New anti H. pylori drug

4- Choose the correct statement about ondansetron:

A a) It is a dopamine D2 receptor antagonist B b) It suppresses postoperative nausea and vomiting C c) It is the most effective antiemetic for motion sickness D d) It is not effective by oral route

5- Vomiting during pregnancy can be treated by:

A a) Ondansetron B b) Cortisone C c) Mitochlopramide D d) Vitamin B6

6-Chlorpromazine and its congeners not used to suppress vomiting of following etiologies :

A a) Motion sickness B b) Radiation sickness C c) Postanaesthetic D d) Uremic

7-Cancer chemotherapy induced vomiting that is not controlled by metoclopramide alone can be suppressed by combining it with:

A a) Amphetamine B b) Dexamethasone C c) Hyoscine D d) Cyclizine

8- Mosapride enhances gastrointestinal motility by:

A a) Activating serotonin 5-HT4 receptor B b) Activating muscarinic M3 receptor C c) Blocking dopamine D2 receptor D d) Blocking M1 receptor

1- The drug of choice for the treatment of tissue amoebiasis:

A a) Paromomycin B b) Metronidazole C c) Diloxanide furoate D d) Tetracycline

2- Metronidazole is used in treatment of:

A a) Trichomonas vaginitis B b) Pneumonia C c) Typhoid fever D d) Influenza

3- The luminal amebecide drug is:

A a) Mebendazole B b) Emetine C c) Chloroquine D d) Diloxanide furoate

3- The luminal amebecide drug is:

A a) Mebendazole B b) Emetine C c) Chloroquine D d) Diloxanide furoate

4- Disulfiram like effect occurs with the following drug if taken with alcohol:

A a) Metronidazole B b) Emetine C c) Chloroquine D d) Diloxanide furoate

5-Which one of the following antiamoebic drugs used in treatment of helicobacter pylori (H.pylori):

A a) Metronidazole B b) Emetine C c) Chloroquine D d) Diloxanide furoate

6- The following drug is effective in hepatic amoebiasis but not in intestinal amoebiasis:

A a) Chloroquine B b) Emetine C c) Tetracycline D d) Diloxanide furoate

7- Pseudomembranous colitis can be treated by the following drug:

A a) Metronidazole B b) Emetine C c) Mebendazole D d) Diloxanide furoate

8- The following drug is used in treatment of bilharziasis:

A a) Metronidazole B b) Albendazoe C c) Praziqantel D d) Flubendazole

9- The following drug is used in treatment of ascariasis :

A a) Metronidazole B b) Albendazole C c) Praziqantel D d) Bithionol

10- In addition to amoebiasis, metronidazole is used for:

A a) Roundworm infestation B b) Hookworm infestation C c) Fascioliasis D d) Giardiasis

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