Quiz: Internal Medicine

Combined uses of statins and fibrates have great chance for

A Peripheral neuropathy B Osteoporosis and osteomalecia C Acute pancreatitis D Muscle injury and rhabdomyolysis

First-line therapy in paret disease is

A Bisphosphonates B Calcium and vitamin D C Tenparatide D Denumaty

Biochemical finding in Osteoporosis:

A Serum levels of calcium, phosphate, and alkaline phosphatase are normal B Calcium and phosphorus levels are low or low-normal and the serum alkaline phosphatase level is increased C Alkaline phosphatase level is elevated while calcium, phosphat hydroxyvitamin D levels are normal D Serum levels of calcium, phosphate and PTH are elevated

Monoclonal antibody against PCSK9 (acts to reduce hepatocyte LDL receptor expression). Very effective in reducing LDL

A Alirocumab and Evolocumab B Denusomab C Omalisumab D Eculizumab

In Osteomalacia

A Bone matrix decreased B Bone matrix intact, mineral decreased C Osteolytic bone lesion D Chaotic osteoclast function with increased bone remodeling

Most common secondary cause for osteoporosis is

A Glucocorticoid use equivalent to 5 mg or more of prednisone per day for 3 or more months B More months C Hyperthyroidism D Smoking

Gold standard for diagnosis of osteoporosis is

A Radiography: bone X-ray B Dual-energy x-ray absorptiometry (DXA) C Chemistry panel including calcium phosphorus, alkalip D Vitamin D levels greater than 20 ng/ml

Features of Addison's disease do not include

A Diarrhea B Dizziness C Dermatitis D Dehydration

Addison's disease is characterized by all of the following EXCEPT:

A Skin pigmentation B Asthenia C Hypokalemia D Hypotension

Otitis fibrosa cystica is associated with

A Addison's disease B Hypothyroidism C Hyperparathyroidism D Hyperthyroidism

All of the following are side effects of prolonged use of cortisone EXCEPT

A Anemia B Growth retardation C Muscle wasting D Increased susceptibility to infection

Which is NOT a part of metabolic syndrome X

A Hyperlipidemia B Obesity C Ischemic heart disease D Hypertension

The triad of hyponatraemia, haemodilution and urine hypertonic to plasma suggest diagnosis of

A Nephrotic syndrome B SIADH C Nephrogenic diabetes insipidus D Addison's disease

Nephrogenk diabetes insipidus may develop due to all except:

A Cystinosis B lithium-induced C Chronic hepatities D Heavy metal poisoning

Osmorec:eptors are present in:

A Atria B Kidney C Anterior hypothalamus D Adrenal cortex

Orlistat is used to treat:

A Diabetic neuropathy B Obesity C Pseudohypoparathyroidism D Anorexia nervosa

Syndrome of inappropriate anti.diuretic hormone (SIADH) may be seen in all except:

A Guillain-Barre syndrome B Subacute bacterial endocarditis C Myxoedema D Bronchogenic carcinoma

Regarding syndrome of inappropriate anti.diuretic hormone (SIADH), which is true?

A Hyponatremia is dilutional B Urine is relatively hypertonk to plasma C ADH-rnediated water reabsorption does not occur D Renal function is jeopardized

In injury to adrenal cortex, secretion of which is least affected?

A Adrenaline B Cortisol C Androstenedione D Aldosterone

An 18-year-old woman reports a 6-week history of fatigue, nausea, involuntary weight loss, and darkening of the skin. Which one of the following tests is the most helpful for establishing the diagnosis?

A Adrenocorticotropic hormone (ACTH) stimulation test B Serum prolactin test C Serum potassium test D 24-Hour urine free cortisol test

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