Quiz: Physiology

Which of the following is not found in plasma?

A a) Albumin B B) Glucose C C) Sodium D d) Hemoglobin

2- Which component of blood makes up most of the blood volume?

A A) Plasma B B) Leukocytes C C) Erythrocytes D d) Platelets

Which organ synthesizes new erythrocytes?

A a) Liver B B) Kidney C C) Spleen D d) Bone Marrow

Which of the following classes of leukocytes function(s) in phagocytosis?

A A) Neutrophils only B b) Lymphocytes onlya C C) Basophils only D d) Neutroĺphils and basophils

Which class of leukocytes develops into macrophages in tissue?

A a) Neutrophils B b) Eosinophils C c) Basophils D d) Monocytes

Which class of leukocytes has granules that stain preferentially with a red dye?

A a) Neutrophils B B) Basophils C C) Eosinophils D d) Monocytes

Which cytokine stimulates erythrocyte production?

A a) ADH B b) Erythropoietin C C) Von Willebrand factor D d) Renin

Which class of blood cell is the most abundant?

A a) Erythrocytes B b) Neutrophils C c) Basophils D d) Monocytes

Contact of blood with collagen triggers.

A a) Platelet aggregation. B b) Activation of the intrinsic clotting cascade. C c) Activation of the extrinsic clotting cascade. D d) Both a and b

What is the function of plasmin?

A A-Stimulate vasoconstriction of damaged blood vessels B b) Inhibit platelet aggregation in healthy blood vessels C c) Activate thrombin D Activate platelet aggregation

The activation of facier X occurs in

A A- the intrinsic pathway only B b. the extrinsic pathway only. C c. neither the intrinsie nor extrinsic pathway. D d. both the intrinsic and extrinsic pathways

Platlets

A A-form a plug by sticking to each other. B b release chemicals thal stimulate vasoconstriction C C-provide phospholipids needed for the intrinsic pathway D D- serve all of these Functions

Which of these sintements about plusmin is true?

A a. It is involved in the intrinsic clotting system. B b. It is involved in the extrinsic clotting system. C c. It functions in fibrinolysis. D d. It promotes the formation of emboli,

Regarding bleeding time which of the following is correct.

A A-Prolonged in prolonged antibiotic therapy. B B-Decreases in liver diseases. C C- Prolonged in hypercholesterolemin. D D- Prolonged in thrombocytopenia.

Regarding erythropoietin hormone which of the following is correct?

A A- Secreted by juxta-glomerular cells. B B-Stimulates thrombocytes formation. C C- Secreted by renal tubular epithelium. D D- Secreted by endothelial cells of peritubular capillaries.

Immunoglobulin G (IgG) has:

A A-4 heavy chains. B B-4 light chains C C-2 heavy & 2 light chains. D D- None of the above.

The coagulation time is prolonged in :

A A-Haemophilia. B B- Anaemia. C C- Polycythaemia. D D- Purpura.

Removal of the stomach can lead to all the following except:

A A- Marked digestive disturbances. B B- Megaloplastic anemia. C C-A fall in the plasma volume after a heavy meal. D D. Diminished Ca++ absorption and weak development of bones.

About Interferon, all the following is true except:

A A . The alpha interferon is released by leucocytes. B B-They activate viruses and stimullate cell proliferation, C C- The beta interferon is released by libroblasts, D D- The gamma interferon is released by the T-lymphocytes and NK cells.

A/G ratio Is Important in detecting:

A A. Cardiac disease B B. Nervous disease C C. Liver disease D D. Lung disease

A patient with platelet count 375000 /cubic mm and bleeding time 7 minutes, what mould you expect:

A A. Defective platelet function B B. Decreased platelet production C C. Increased platelet production. D D. Increased platelet function

Microcytic hypochromic anaemia occurs in;

A A. Vit B12 deficiency B B. Autoimmune hemolytic anemia C C. Iron deficiency anemia D D.Acute bleeding

A reduction of the blood level of factor VIII:

A A. Increase the bleeding time beyond the normal range. B B. Is a hereditary disease due to an abnormal gene on the Y chromosome.. C C. Causes prolongation of the clotting time. D D. Is commonly associated with petechial haemorrhage in the skin.

Increased RBCs fragility securs in all the following except:

A A.Sickle cell anemia B B. Thalassaemia C C. Iron deficiency anemia D D.Heriditary spherocytosis

heparin is anticoagulant:

A A.In vitro B B. In vivo C C. Both A&B D D.None of the above

A female carrier of haemophilia married too haemophilic male may produce any of the following except:

A A.A normal daughter B B.A carrier daughter C C.A haemophilic daughter D D.A haemophilic )

The concentration of Hb in ench RBC per deciliter is:

A A) 6 3 picograms. B b) 32 picograms. C c) 33 picogram. D d) 30 picogram.

Lack of intrinsic factor causes:

A a) Megaloblastic anemis. B b) Pernicious anemia. C C) Aplastic anemia D D) Thalassaemia

The normal volume of blood of a man weighing 70 kgs is:

A a) 2lit B B) 4.5 lit C c) 5.6 lit D d) 6.0 lit

Osmotic pressure exerted by plasma proteins, influence the exchange of:

A a. Gasses between blood and tissues. B b. Fluid between blood and tissues C c.Nutritive materials D d. Diapedisis.

Majority of clotting factors are produced in :

A a) Liver B b) Kidney C c) Heart D d) Brain

iron is stored in the body in the following EXCEPT:

A A) spleen B b) reticuloendothelial system C c) gall bladder D d)bone marrow

:Action of plasmin is:

A a) to remove calcium B b) antithrombin action C c) to stimulate heparin D d) to degenerate librin

Osmotic pressure of plasma is mainly maintained by :

A a) Albumin B b) alpha globulin C c) gamma globulin D d) prothrompin

Which is the most rare blood group?

A a) A Rh+ B b) AB Rh+ C c) AB Rh- D d) B Rh-

The relative proportion Hb in red cell is shown by:

A a. Colour index. B b. MCV, C c. MCHC. D d. PCV.

The synthesis of Hb begins in the:

A A) Basophil erythroblast. B b. Ortho erythroblast C c. Chromophil erythroblast D d. Reticulocyte.

Calcium is essential for all of the following steps in the clotting EXCEPT:

A A) Activation of factor XI by factor XII. B b. Activation of factor IX by factor XI. C c. Activation of factor X by factor IX. D d. Formation of thrombin from prothrombin.

The group which has no agglutinogen is:

A A) A group. B b) B group. C c) O group. D d) AB

Calcium is essential for all of the following steps in the clotting EXCEPT:

A A. Activation of factor XI by factor XII. B b. Activation of factor IX by factor XI. C c. Activation of factor X by factor IX. D d. Formation of thrombin from prothrombin.

14 is said to be agglutinated when the:

A a. RBCs are separated B b. RBCs are clumped together C c. WBCs are clumped together D d. Platelets are clumped together

During starvation plasma proteins are formed from:

A a. Tissue proteins. B b. Blood C C. Liver D d. Kidney

Blood platelets :

A A. Increase in number after injury. B B. Have a small single lobed nucleus C C. about 5 million /cubic mL D D. Are normally more numerous than white blood cells .

The commonest Rh antigen is:

A a.C B b. A C c. D D d. B

Edema is caused by the deficiency of:

A A-Albumin B b. a-globulin. C C-B-globulin D d. Fibrinogen

The main function of globulin Is:

A a. Maintenance of osmotic pressure. B b. Defense mechanism. C C.Water balance. D d. Iron balance.

46- Substance which causes platelets activation is :

A a. Fibrinogen. B b. Damaged collagen. C c. Prothrombin. D d. Prothrombin activation.

Prothrombin time in the plasma is prolonged by the administration of:

A A. Vit K. B b. Calcium glycinate. C c. Dicoumeral. D d. Folic acid.

Haemoglobin contains:

A A. One pratopoephorin ring and 4 ferrous ions B B. Four protoporphorin ring and one ferrous ion C C. Four protoporphorin rings and four ferrous ions D D.One pratoporphorin ring and one ferrous ian

Erythrocytes

A A. Are responsible for the major part of blood viscosity B B.Contain the enzyme carbonic anhydrase C C. Increase heir volume in hypertonic saline D D. Burst when mixed with 0.9% saline.

During the immunization against infective diseases the fraction of plasma which Increnses:

A a. Albumin. B b. Globulin. C c.Fibrinogen. D d.Prothrombin.

Synthesis of Hb occurs in the:

A A)Mitochondria B b) Gogi apparatus C c) Nucleus D d) Food vacuales.

The plasma proteins perform all the following functions EXCEPT:

A A)They exert an osmotic force. B b) They have buffering action. C c) They help maintenance of the arterial blood pressure. D d) They play no role in the body defense mechanisms.

The postpituitary hormone that is responsible for water balance is:

A a. Vasopressin B b. Oxytocin C C. Prothrombin D d.prolactin

The hormone which regulates the water balance through electrolytes is:

A A. Aldosterone B b.Vasopressin C C. Oxytocin D d.Progesterone

The addition of sodium citrate to banked blood Inhibits coagulation. By what mechanism Do citrate ions inhibit coagulation?

A A. Antagonist to adenosine diphosphate B B. Antagonist to thromboxane A2 C C. Chelates Ca2+ ions D D. Binds to factor VII

Platelets play an important role in the:

A a. Haemolysis B b. Haemopoiesis C c. Haemostasis D d. Homeostasis

The normal life span of platelets is:

A A. 8-10 days B B. 8-10 hours C C. 8-10 weeks D D. 8-10 months

The anticoagulants which act both in vivo and vitro are:

A a) Heparin B b) Oxalate C c) Citrate D d) All

Failure of maturation of RBC is due to poor absorption of:

A a) Folic acid B b) Vit B12 C c) Zinc D d) a and b

Red bone marrow is absent in:

A a) Pernicious anemia B b) Sickle cell anemia C c) Aplastic anemia D d) Megaloblastic anemia

In Polycythemia the blood shows:

A Increased volume B Increased viscosity C Decreased velocity D All the above

In anemia the blood shows:

A Increased viscosity B b. Increased resistance C c- Decreased viscosity D non of the above

Symptoms of erythroblastosis foxtails is:

A Anemia B b. Jaundice C Oedema D All

Cyanosis is caused when the reduced Hb concentration of blood in capillaries is more than:

A a) 3mg/dl B b) 5mg/dl C c) 10mg/d1 D d) 12mg/dl

In pernicious anemia the color index is:

A a. More than one B b. Less than one C c. Equal to one D d. All

The number of oxygen molecules carried by one Hb molecule

A a) 1 B b) 2 C c) 4 D d) 8

The intrinsic factor:

A A) Is found in the liver. B B) Is produced by the gastric parietal cells. C C) is secreted by the terminal ileum. D D) Aids absorption of folic acid.

All the following substances are essentist for the normal development of R.B.Cs EXCEPT:

A A. Folinic acid. B B. Ascorbic acid. C C. Nicotinic acid. D D. Cyanocobalamin.

Physiological polycythemia is seen in persons living at:

A a) High altitudes B b) Low altitudes C c) Planes D d) Mines

A person having pinkish tint to the skin may be suffering from:

A a. Anemia B b. Eosinophilia C c. Leukemia. D d. Polycythemia.

A person having pinkish tint to the skin may be suffering from:

A a. Anemia B b. Eosinophilia C c. Leukemia. D d. Polycythemia.

The breakdown of erythrocytes in the body gives

A A. iron, most of which is excreted in urine B B. water soluble bilirubin C C. bilirubin which is conjugated in the kidney. D d. amino acids used in protein resynthesis.

Which of the following is correct concerning erythrocytes?

A a. Are responsible for the major part of blood viscosity B b. Contain small central nucleus C c. Their volume increases in hypertonic saline D d. Burst when mixed with 0.9% saline

Circulating red blood cells

A A. include intermediate normoblasts. B B. are mainly reticulocytes. C C. are distributed evenly in the blood stream. D D. are deformed as they pass through the capillaries.

Blood

A A. each Kg body weight represents 20-50 ml of blood/ B B. comprises a higher percentage of body weight in obese than in slim persons. C C. volume can be calculated by multiplying plasma volume by hemoglobin concentration. D D. serum is plasma minus clotting factors.

Red blood cell production is increased in the following conditions EXCEPT :

A a- decreased oxygen tension in arterial blood B b- one week after blood donation C c- anemia duo to excess hemolysis. . D d- erythropoietin in patients with ESRD

The primary factor that regulates erythropoietic activity is

A a. the kidney B b. erythropoietin C c. the erythroid colony-forming unit (CFU-E) D d. oxygen

Haem contains a pure pigment known as:

A A) Porphyrin. B B) Chlorophyl. C C) Carotin. D D) Bile

Rericulacytes are increased in the following conditions:

A a) Before hemorrhage. . B b) After hemorrhage C c) Lack of vitamin. D d) Lack of proteins.

Pernicious anemia is:

A a. Microcytic hypochromic anemia. B b. Microcytic hyperchromic anemia. C c. Macrocytic anemia. D d. Normocytic anemia.

Pernicious anemia is:

A a) Blood clotting. B b) Leukopoiesis. C c) Formation of prothrombin. D d) Formation of red blood corpuscles.

Sickle cell anemia is commonly seen in:

A a. India. B b. America. C c. Europe. D d. Africa.

Total gastrectomy will lead to:

A A. Aplastic anemia B B. Megaloblastic anemia C C. Sickle cell anemia D D. Thalassemia

The viscosity of blood depends on concentration of:

A a. RBC. B b. WBC. C c. Platelets. D d. None of the above.

The viscosity of blood depends on concentration of:

A a. Aplastic anemia. B b. Thalassemia. C c. Pernicious anemia. D d. Sickle cell anemia.

The major constituent of plasma protein is:

A a-globulin. B b-Albumin. C c-globulin. D d-Fibrinogen

The albumin/globulin ratio is:

A A. 2:1 B B. 1:2 C C. 1:1.5 D D. 1:1

In liver disease albumin globulin ratio is;

A A. Increases. B B. Decreases. C C. Reverted. D D. Not altered.

Antibodies belongs to the class:

A A. Gamma globulins. B B. globulins C C. Fibrinogen D D. globulin.

The protein exerting maximum osmotic effect is:

A a) Albumin B b) Globulin C c) Fibrinogen D d) Prothrombin.

Gamma globulin is synthesized by:

A A. Liver. B B. Plasma cells. C C. Reticuloendothelial. D D. Kidney

The degraded albumin is eliminated by:

A A. Blood. B B. Kidney. C C. Spleen. D D. Lungs

The colloid osmatic pressure exerted by plasma proteins is called:

A a) Oncotic pressure. B b) Blood pressure. C c) Both of the above D d) None of the above

When fully saturated I gm of Hb combines with:

A a. 1.15 ml of oxygen. B b. 2.16 ml of oxygen. C c. 1.30 ml of oxygen D d. 1.34 ml of oxygen.

The haemoglobin, Oxyhsemoglobin buffer system is an effective method for buffer :

A a. Acetic acid. B b. Amino acid, C c. Carbonic acid. D d. Hydrochloric acid

Incompatible blood transfusion may cause the following EXCEPT:

A a) Anuria B b) Hypertension C c) Fever D d) Hemolytic jaundice

All the following conditions cause anemic EXCEPT:

A a) Erythroblastosis fetalis. B b) Destruction of the bone marrow, C c) Vitamin B12 deficiency. D d) Liying at high attitudes.

The activation of prothrombin into thrombin is achieved by:

A a- Factor X. B b- Factor III C c- Factor VIII. D d- Factor Ix.

About the action of anticoagulants, all the following is true EXCEPT:

A a) Dicumarol interferes with the synthesis of prothrombin in the liver. B b) Oxalates form insoluble salts with Ca. C c) Citrates & other chelating agents bind Ca". D d) Heparin blocks the action of antithrombin III .

Sign in required