2.A 0.7 cm microadenoma of the adenohypophysis is seen by head MRI in a 25-year-old female. Which of the following complications is she most likely to have?

3. Which of the play a role in following hormones, in addition to participating in the initiation of labor, may trust, monogamy, and the desire to cuddle?

4.A 25-year-old woman who has never been pregnant presented with amenorrhea and me discharge from the nipple for 3 months. Investigations revealed that fier serum LH and Erdiol levels are below normal and pregnancy test is negative. Which of the following is the possible underlying cause of her condition?

5.A patient with Cushing syndrome might present with any of the following EXCEPT:

6.41-year old male Wucose intoleran and has a large jaw. You wonder if he might have siamegaly due to a pituitary adenoma. What laboratory test would be best for making this diagnosis?

7. Diabetes insipidus is associated with a lack of:

8. Acromegaly is characterized by an excess of:

9. Which of the following is the most common cause of Cushing's syndrome?

10. Panhypopituitarism may be a manifestation in all of the following conditions EXCEPT

11. A destructive lesion in which of the following areas generally results in diabetes insipidas

12. Which of the following is NOT a manifestation of postpubertal panhypopituitarism?

13. Hypopituitarism is most frequently associated with:

14. Ad 5-year-old boy with no sexual maturation is found to have papilledema, an enlarged e and fine calcifications above the sella on skull x-ray. The most likely diagnosis is

15. The most common cause for acromegaly is:

16. Cushing's disease is distinguished from Cushing's syndrome by the presence of :

17. The most common. Severe postperhouse-Friderichsen syndrome is:

18. Pituitary adenoma may cause:

19. A 4-month-old child is brought to the pediatrician for evaluation. The mother received no antenatal care and states that she has "a thyroid condition". The child has delay development with macroglossia and umbilical hernia. Which of the following is the underlying condition?

20. A 40-year-old female was found to have a solitary nodule in the left side of her neck. A biopsy revealed thyroid tissue within the lymph node. The most likely diagnosis is:

21. Patients with hashimoto thyroiditis are at increased risk of which of the following?

22. All lesions of thyroid Medullary agnosed by fine needle cytology EXCEPT:

23. Difference between follicular carcinoma and follicular adenoma can be made by which of the following?

24 . Which of the following is the earliestmanifestation of medullary carcinoma of thyroid?

25. Antibodies central for graves disease is:

26. Which thyroid cancer is infamous for invading vessels?

27. A 2-year old child has had failure to thrive. The child is short, with coarse fascial features, a otruding tongue, and an umbilical hernia. Profound mental retardation is apparent as the child matures. These findings are best explained by a lack of:

28. A 58-year-old woman presented with thyroid nodule. Examination revealed single, no functioning mass within the thyroid. Histologic sections of the mass show small thyroid follicles surrounded by complete fibrous capsule that compresses the adjacent normal thyroid tissue. Focal invasion into the capsule is found. Which of the following is consistent with these findings?

29. A 60-year-old woman has been feeling tired and sluggish for long time. Thyroid gland is not palpable. Serum 14 level is decreased but TSH is markedly increased. Which of the following factors is important in the pathogenesis of this condition?

30. During examination a 45 years old man is noted to have a 3 cm palpable nodule in one lobe of the thyroid gland. Needle aspiration of the nodule demonstrates polygonal tumor cells and amyloid. Which of the following is the most likely diagnosis?

31. Which of the following is true of papillary thyroid carcinoma?

32. The most common cause of hypothyroidism in under-developed countries is:

33. Your sister is complaining that she is always tired, despite getting enough sleep. You notice that she seems pale, and when you feel her pulse it is quite slow. She also mentions that she can't stand the cold these days. What two lab tests would be most helpful in diagnosing her condition?

34. A 37-year-old man presented with a single firm mass within the thyroid gland. Histologic examination of the massrevealed an organoid nests of undifferentiated malignant tumor cells separated by broad bands of stroma. The stroma stains positive with congo red stain. Which of the following is consistent with these findings?

35. Which of the following neoplasms is the most likely to be familial?

36. The first endocrine target organ to be affected by panhypopituitarism is:

37. Histological changes in the thyroid gland in response to excess TSH stimulation includeof the following EXCEPT:

38. Which of the following is the characteristic findings in patients with Hashimoto's thyroi ?

39. Which of the following represents the microscopic appearance of the thyroid gland following effective treatment of Graves' disease?

40.Features of primary hyperthyroidism include:

41. All of the following are associated with Graves' disease EXCEPT:

42. Deficiency of thyroid hormone in the adult is associated with which of the following?

43. Which of the following is the most common midline cyst of the neck?

44. The histologic appearance of the thyroid gland in treated Graves' disease consists of

45.Features of BOTH Hashimoto's and granulomatous thyroiditis include

46.Multi-nodular goiters may assume clinical importance for all of the following reasons EXCEPT:

47.Thyroglobulin antibodies are most likely to be present in patients with:

48.Which of the following best describes the histologic appearance of the thyroid gland in colloid nodular goiter?

50- Exophthalmos is characteristically associated with:

51-A36-year-old woe. Follicular carcinomal enlargement of the thyroid gland approximate weeks after an uppetices Rory infection. The history is most suggestive of which ofthe following findings on biopsy of the thyroid?