Quiz: Another Exams

1-EndocrinaI disorder due to.

A B -Hypo secretion B A-Hyper secretion C C-all of the above D D-hormone resistance

2-Acromegaly due to

A A-Increase growth hormone secretion B B-Decrease growth hormone secretion C C-Increase thyroxin D D- All of the above

3-Thyroid disorders are

A Myxedema B Hyperthyrodism C C-None of the above D D-Both a and b

4-Hyper secretion of catecholamine is

A A-Cushing syndrome B B-pheochromocytom C Myxedema D D-None of the above

5. Regarding thyroid gland following are true except:

A A. Highly vascular organ B B. Consists of right and left lobes connected by isthmus C C. Isthmus related to 1 st, 2 nd and 3 rd tracheal rings D D. Each lobe is pear in shape

6. Cortex of suprarenal gland is derived from

A A. Mesoderm B B. Neural crest C C. Endoderm D D. Mesonephric duct

7. The most apparant feature of thyrotxicosis:

A a) Muscle wasting. B b) Pretibial myxedema. C c) Exopthalmos. D d) Palpitations.

8. Thyroid carcinoma not include

A a) Papillary B b) Follicular C c) Anaplastic D e) Warthin tumors

9. The master gland of the endocrine system is:

A a. Thyroid B b. Liver C c. Pituitary D d. Brain

10. As regarding pheochromocytoma. Which is correct:

A a. High grade malignant tumor B b. Secretes adrenaline and causing hypertension C c. Capsulated tumor of parathyroid gland D d. Increases intracranial tension

11-The following is not anterior pituitary hormone:

A a- Growth hormone B b- Prolactin hormone C c- Oxytocin D d- FSH

12-Gigantism should be treated by the following:

A a- Octreotide B b- GH C c- Prolactin inhibitors D d- Thyroxine

13-Infertility is not treated by the following:

A a- Human chorionic gonadotropines B b- Progesterone C c- Human menopausal gonadotropines. D d- Bromocriptine.

14- Oxytocin is not used in the following:

A a- Induction of labor B b- Incomplete abortion. C c- Post partum hemorrhage D d- Contracted pelvis

15- Insulin is not given orally because:

A a- It is destroyed by gastric pepsin. B b- It is gastric irritant. C c- It is destroyed by first pass effect. D d- It is acid sensitive

16-Hyperthyroidism is treated by the following drug to prevent sympathomimetic manifestations:

A a- Antithyroid drugs B b- Propranolol C c- Adrenaline D d- Verapamil

17. Hypoglycemia comes about for various reasons and clinical symptoms usually occur at blood glucose concentrations:

A a. <3.8mmol/L B b. < 3.0mmol/L C c. <2.8mmol/L D d. <5.0mmol/L

18. The healthy organism maintains the extracellular glucose concentration remarkably constant within the limits of:

A a. 5-12mmol/L B b. 3.3 - lOmmol/L C c. 2.8- 3.8mmol/L D d. 1.2- 2.4 mmol/L

19-Effect of calcitonin on mineral metabolism

A a. inhibition of calcium mobilization from bones B b. bone mobilization C c. increased calcium reabsorption in the kidney D d. reduced phosphate reabsorption in the kidney

20-Vasopressin is a hormone that has a powerful antidiuretic effect, stimulating the reverse flow of water through the membranes of the renal tubules. What is its chemical nature?

A a. Steroid compounds B b. Carbohydrate C c. Derived amino acid D d. Peptide

21.Action of physiological concentrations of thyroxine:

A a. increase synthesis of nucleic acids and proteins B b. increase deposition of calcium and phosphate in bones C c. regulate water metabolism D d. stimulate secretion of thyroid hormones

22.Action of high concentrations of thyroxine:

A a. activate anabolism B b. activate catabolism C c. decrease body temperature D d. decrease appetite

23.Addison’s disease is caused by the damage of:

A a. thyroid gland B b. hypophysis C c. adrenal medulla D d. adrenal cortex

24.Role of cyclic AMP in the cell:

A a. is converted to ATP B b. activates adenylate cyclase C c. is source of energy D d. activates protein kinase A

25-A1I of the following are true about growth hormone except it:

A A Increases protein synthesis B B Increases Bl. glucose level C C Stimulates formation of "Somatomedine" in the liver and kidney D E Is stimulated by Hyperglycemia

26-All of the following are actions of oxytocin except it:

A A Helps milk ejection B B Inhibit uterine contraction at end of pregnancy C C Involution of the uterus as before pregnancy D D Prevention of post-partum heamorrhage

27)-All of the follow ing are not action of thyroxin except it:

A A Decreases the metabolic activities in most tissues of the body B B Increases blood glucose level C C Decreases the free fatty acid level in blood. D D Decreases protein synthesis in the cells

28)-All of the following hormones increase plasma calcium level except:

A A Growth hormone B B 1,25-dihydroxycholecalciferol C C Cortisol D D Parathormone

29) All of the following are correct about Osteoblasts except they:

A A Are the bone cells concerned with bone formation B B Synthesize the proteins called matrix gla protein and osteopontin C C Are the bone cells concerned with maintenance of bone D D Are rich in enzyme alkaline phosphatase

3O)-A11of the following are actions of cortisol except it:

A A Stimulates the inflammatory changes B B Produces Na- and H2O retention C C Increase general metabolism D D Increases blood glucose level

31- All of the following are correct about insulin action except it:

A A Stimulate gluconeogenesis B B Facilitates of glucose transport into most cells C C Stimulates of glycogenesis in liver and muscles D D Is not needed for glucose uptake by the liver, brain and working muscles

32) In absence of , serum K+ level increased

A A Renin B B Calcitonin C C Parathormone D D Aldosterone

33-How do hormones from the thyroid and parathyroid regulate the calcium concentration of the blood?

A A Calcitonin lowers blood calcium: parathyroid hormone raises blood calcium. B B Parathyroid hormone lowers blood calcium; calcitonin raises blood calcium. C C Thyroxine and triiodothyronine together regulate calcium levels D D Both parathroid hormone and the three thyroid hormones function to regulate blood calcium levels.

34-All of the following are correct about melatonin except it:

A A Is secreted by the parenchymal cells of pineal gland B B It stimulates the onset of puberty by stimulating the gonads. C C Secretion of melatonin is more in darkness than in daylight D D Hypothalamus is responsible for the circadian fluctuations of melatonin secretion

35- GH secretion is inhibited by:

A A Hypoglycemia B B Fasting C C Starvation D E Later stages of sleep

36-Leptin is secreted by:

A Skeletal muscle B Kidney C Adipose tissue D Liver

37- The role of chromogranins in the adrenal medulla

A a) Activation of endoplasmic reticulum B b) Regulation of gene expression C c) Inhibition of apoptosis D d) Binding to catecholamines

38- Which is TRUE about pinealocytes?

A a) Secrete melanin B b) Large multinucleated cells C c) They contain corpora arenacea D e) Communicate with each other by junctions

39- Immuno-fluorescence image shows insulin-secreting B cells of pancreas:

A A. Green. B B. Red. C C. Brownish orange. D D. Blue.

40AU of the followings are cells of adenohypophysis of pituitary gland EXCEPT:

A A. Somatotrophs B C. Thyrotrophs C B. Mammotrophs D E. Parafollicular (C) cells

1. Parathyroid gland lies on :

A A.posterior surface of thyroid B B.medial surface of thyroid C C.lateral surface of thyroid D D.all of above

2. Thyroid isthmus lies in front of :

A A.2-3-4 rings of trachea B B.3-4-5 rings of trachea C C.3-4 ringed of trachea D D.larynx

3-Causes of thyrotoxicosis is

A a-hyper function of thyroid gland B b-drug induce C c-both a and b D d-none of the above

4-Hyper secretion of catecholamine is

A a-Cushing syndrome B b-pheochromocytoma C c-myxedema D d-none of the above

5-Acromegaly due to

A a-increase growth hormone secretion B b-decrease growth hormone secretion C c-increase thyroxin D d- all of the above

6-Thyroid disorders are

A a-myxedema B B-hyperthyrodism C c-none of the above D d-both a and b

7- Sheehan’s syndrome is caused by:

A a) Pituitary adenoma B b) Postpartum necrosis of pituitary' C c) Postmortem pituitary incidentaloma D d) Autoimmune hypophysitis

8- Pituitary adenoma after closure of epiphysis leads to:

A a) Gigantism B b) Acromegaly C c) Pituitary dwarfism D d) Myxoedema

9- Hurthle cells or Askanazy cells are usually seen in:

A a) Toxic goiter B b) Multinodular colloid goiter C c) Hashimoto’s thyroiditis D d) Subacute granulomatous thyroiditis

10- Nodular colloid goiter occurs when there is:

A a) Iodine deficiency for a long period B b) Iodine deficiency for a short period C c) Repeated iodine deficiency and correction D d) Autoimmune destruction of thyroid follicles

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