Quiz: Pharmacology

1-Female sex hormones are formed in the following sites:

A a-ovaries B b-adrenal cortex C c-testes D d-all of the above

2-Female sex hormones synthesis and release are controlled by:

A a-blood level of female sex hormones B b-pituitary FSH& LH. C c-both of the above D non of the above

2-Female sex hormones synthesis and release are controlled by:

A growth of the mammary duct system during puberty. B growth & development of vagina,uterus and fallopian tube. C development of secondary female sex characters. D calcium deposition on bones& bone growth during puberty.

3-Pharmacological actions of estrgen irclude the following except:

A a-growth of the mammary duct system during puberty. B .b-growth & development of vagina,uterus and fallopian tube. C c-development of secondary female sex characters. D .e-catabolic action.

3-Pharmacological actions of estrgen irclude the following except:

A a-growth of the mammary duct system during puberty. B .b-growth & development of vagina,uterus and fallopian tube. C c-development of secondary female sex characters. D .e-catabolic action.

3-Pharmacological actions of estrgen irclude the following except:

A a-growth of the mammary duct system during puberty. B .b-growth & development of vagina,uterus and fallopian tube. C c-development of secondary female sex characters. D .e-catabolic action.

3-Pharmacological actions of estrgen irclude the following except:

A a-growth of the mammary duct system during puberty. B .b-growth & development of vagina,uterus and fallopian tube. C c-development of secondary female sex characters. D .e-catabolic action.

4-The folowing are therapeutic uses of estrogen except:

A .a- in combination with progesterone as oral contraceptives. B b-high doses of estrogen are used for post coital contraception. C c-it may be used in postmenopausal syndrome & osteoporosis. D . .e-it is used as an injectable contraceptive.

: 5-The following are therapeutic uses of estrogen are true except:

A a-postmenopausal cancer breast. B b-cancer prostate in males. C c-premenopausal cancer breast D d-functional uterine bleeding & menstrual disturbances

6-Adverse effects of estrogen include the following except:

A a-increased salt&water retention,rise of bl. p&weight gain B b-it increases blood coagulability C c-it may increase blood glucose and lipoproteins. D e-none of the above.

6-Adverse effects of estrogen include the following except:

A a-increased salt&water retention,rise of bl. p&weight gain B b-it increases blood coagulability C c-it may increase blood glucose and lipoproteins. D e-none of the above.

7-Adverse effects of estrogen include the following except:

A a-nausea and vomiting. B b-loss of hair. C c-menstrual disturbances. D e-all of the above.

8-Regarding to the adverse effects of estrogen the following is true:

A a-increased salt and water retention B b-rise of blood pressure C c-weight gain. D d-all of the above

8-Regarding to the adverse effects of estrogen the following is true:

A a-increased salt and water retention B b-rise of blood pressure C c-weight gain. D d-all of the above

9-The following are adverse effects of estrogen except:-

A a-precipitation of thromboembolic disorders. B b-it may increase blood glucose&lipoproteins. C c-it may increase the risk of endometrial carcinoma. D d-none of the above.

10-Contraindications of estrogen include the following:

A a-thromboembolic diseases. B b-diabetes C c-hyperlipoproteinemia. D e-all of the above

11-Contraindications of estrogen include the following:

A a-hypertension& cardiovascular diseases. B .b-migraine. C c-premenopausal cancer breast&endometrial fibroids. D d-all of the above.

: 12-Tamoxifen is a competitive antagonist of estrogen:

A a-true B b-false C .. D ..

13-Regarding to progesterone the following is true:

A .a-it is responsible for the secretory phase of menstrual cycle. B b-it is released mainly in the second half of the menstrual cycle C .c-it promotes development of the mammary gland acini. D d-all of the above

14-Regarding to progesterone the foliowing are true except:

A a-it prepares the endometrium for the implantation of the fertilized ovum. B b-development of secondary female sex characters C c-it relaxes the pregnant uterus. D d-its administration leads to mild hypothermia.

15-The following are therapeutic uses of progesterone except:

A .a-menstrual disturbances and functional uterine bleeding. B b-as a contraceptive (oral pills, long acting intramuscular injections& long acting s.c.capsules) C c-with estrogen as oral combined contraceptive. D d-as a post coital contraceptive

15-The following are therapeutic uses of progesterone except:

A .a-menstrual disturbances and functional uterine bleeding. B b-as a contraceptive (oral pills, long acting intramuscular injections& long acting s.c.capsules) C c-with estrogen as oral combined contraceptive. D d-as a post coital contraceptive

23-Adverse effects of contraceptives include the following except:

A a-changes in plasma levels of lipids. B b-breast engorgement C c-CNS depression D d-hair growth.

24-Oral contraceptives antagonize the action of:

A a-oral anticoagulants B b-atropine C c-adrenaline D d-prazosin

25-The following drugs inactivate female sex hormones except:

A a-barbiturates B b-rifampicin& ampicillin C c-carbamazepine& phenytoin D e-chloramphenicol

16-Adverse effects of progesterone include the following:

A a-salt& water retention,rise of blood pressure B b-weight gain C c-thrombophlebitis,deep venous thrombosis. D d-all of the above

: 17-Adverse effects of progesterone include the following:

A a-menstrual disturbances. B b-hepatitis& jaundice. C c-hair loss. D d-all of the above

: 17-Adverse effects of progesterone include the following:

A a-menstrual disturbances. B b-hepatitis& jaundice. C c-hair loss. D d-all of the above

: 18- Contraindications of progesterone include the following:

A a-organic heart diseases B b-hypertension C c-thromboembolic diseases D d-al of the above

:: 19-Contraindications of progesterone include the following except:

A a-hepatic diseases B b-hyperlipoproteinemia C c-endometrial fibromas& cancer breast. D d-none of the above

:: 19-Contraindications of progesterone include the following except:

A a-hepatic diseases B b-hyperlipoproteinemia C c-endometrial fibromas& cancer breast. D d-none of the above

:: 19-Contraindications of progesterone include the following except:

A a-hepatic diseases B b-hyperlipoproteinemia C c-endometrial fibromas& cancer breast. D d-none of the above

:: 20-The combined oral contraceptives produce the following except:.

A a-thromboembolic complications.. B b-fluid retention C c-rise of blood pressure D d- hypoglycemia

:21-Female sex hormones by inducing fluid retention can aggravate:

A a-congestive heart failure &edema B b-hypertension C c-epilepsy & migraine D d-all of the above.

:22-Adverse effects of contraceptives include the following except:

A a-increased sodium& water retention. B .b-hypotension. C c-increased blood coagulability. D .d-thrombophlebitis.

23-Adverse effects of contraceptives include the following except:

A a-changes in plasma levels of lipids. B b-breast engorgement. C c-CNS depression D d-hair growth.

24-Oral contraceptives antagonize the action of:

A a-oral anticoagulants B b-atropine C c-adrenaline D d-prazosin

24-Oral contraceptives antagonize the action of:

A a-oral anticoagulants B b-atropine C c-adrenaline D d-prazosin

25-The following drugs inactivate female sex hormones except:

A a-barbiturates B b-rifampicin& ampicillin C c-carbamazepine& phenytoin. D d-chloramphenicol

26-The following is not a possible mechanism of hormonal contraceptives:

A a-inhibition of ovulation in the ovary. B b-they thicken cervical secretions& prevent the sperm migration C c-they induce formation of adhesions and block the fallopian tube & prevent sperm-ovum fertilization. D griseod-they produce endometrial changes& prevent ovum implantation fulvin

27-Regarding to combined contraceptives,the following is false:

A a-they can be used to postpone menstruation. B b-they are taken daily from the start of bleeding for 21days. C c-they are contraindicated in heart diseases, hypertension, diabetes and thromboembolic diseases. D d-they should be taken from the 5th day of bleeding.

28-Female sex hormones interfere with the activity of the following drugs except:-

A a-diuretics and antihypertensives B b-antidiabetic drugs C c-hypolipedemic drugs d-anticoagulant drugs D . All True without except

29-Additive fluid retention occurs by using female sex hormones with: y of the following drugs except:-

A NSAIDs B vasopressin C vasodilatorsd-corticosteroids. ,. D all of the above

30-Estrogen& progesterone as an enzyme inhibitor, can inhibit metabolism of

A a-true B b-false C .. D ..

31-Androgen (testosterone) is formed in the following site:

A a-adrenal cortex B b-testes C c-ovaries D d-all of the above

: 32-Androgen stimulates the following:

A growth& development of male genitalia B spermatogenesis. C development of secondary male sex characters D all the above

:33-Androgen produce the following actions except:

A a-stimulation of erythropoiesis B .b-anabolic C c-increase liver synthesis of clotting factors. D d-none of the above

:33-Androgen produce the following actions except:

A a-stimulation of erythropoiesis B .b-anabolic C c-increase liver synthesis of clotting factors. D d-none of the above

34-Regarding to therapeutic uses of androgen,the following is correct:

A in male hypogonadism& delayed puberty.. B as an anabolic drug in males. C in certain types of anemia e.g.aplastic and hemolytic anemia. D e-all of the above

35-Adverse effects of androgens include the following except:

A a-retention of salt and water,edema B b-may decrease blood pressure. C .c-gynecomastia D d-suscebtibility to atheroscleros

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