Quiz: gout — AUA MCQ

1- A 35-year-old male presents with severe pain, swelling, and redness in the left big toe since early morning. There is no history of trauma. The patient is taking a diuretic for hypertension. Which one of the following is the most likely diagnosis in this patient? A.Rheumatoid arthritis B. Gouty arthritis C. Pseudogout D. Septic arthritis Answer: B 2- A 70-year-old male develops the sudden onset of severe left knee pain. The knee is red, swollen, and tender. He has a known case of hyperparathyroidism. An x-ray of the knee shows linear calcification. What is the most likely diagnosis in this patient?

A A. Pseudogout B B. Gout C C. Rheumatoid arthritis D D. Osteoarthritis

3- Which of the following is least likely to be associated with gout?

A A. Thiazide diuretics B B. Rheumatoid arthritis C C. Low dose aspirin D D. Osteoarthritis

4- In a patient with gouty arthritis, which of the following is most useful in establishing the diagnosis?

A A. Serum uric acid B B. Uric acid in urine C C. Urate crystal in synovial fluid D D. Serum calcium level

5- Which of the following joints is most frequently involved in a patient with an acute attack of gout?

A A. Knee joint B B. Ankle joint C C. 1st metatarsophalangeal joint D D. 1st metacarpophalangeal joint

6- Pseudogout has been associated with or encountered in

A A. Hypomagnesemia B B. Hemochromatosis C C. Hyperparathyroidism D D. All of the above

7- A 38-year-old male suffered from redness and swelling of the first metatarsophalangeal joint three times over the past two years. He was found to be hypertensive, and the EEG showed inverted 'T' waves in precordial leads. Which one of the following investigations will be diagnostic?

A A.Rheumatoid factor B B. Serum uric acid C C. ESR D D.Joint fluid aspiration

8- A 50-year-old patient wakes up with excruciating pain at the base of the great toe, with redness and swelling. Which of the following would be the most desirable drug in this patient?

A A. Allopurinol B B. Probenecid C C. Febuxostat D D.Indomethacin

9- Pseudogout can be distinguished from gout by means of

A A. Acute onset B B. Positive birefringent crystals C C. Association with diabetes mellitus D D.Involvement of large joints

10- All of the following statements except one are correct about gout. Which is the exception?

A A. Occurs due to accumulation of urate crystals in joint B B. Can be precipitated by pyrazinamide C C. Occurs more frequently in females D D. Hyperuricemia in primary gout is mainly due to decreased excretion of uric acid

11- Prolonged allopurinol therapy in a patient with gout is indicated in all except one of the following conditions. Which is the exception?

A A. Acute gouty arthritis B B. Tophi C C. Urate nephropathy D D. Evidence of bone /joint damage

12- All of the following except one can be used to prevent attacks of gouty arthritis. Which is the exception?

A A. Allopurinol B B. Aspirin C C. Probenecid D D. Febuxostat

13- All of the following conditions except one are frequently observed in gout. Which is the exception?

A A. Uric acid nephrolithiasis B B. Deficiency of enzyme xanthine oxidase C C. Hyperuricemia D D.Renal disease involving interstitial tissues

14- The crystals isolated from joint in a patient with pseudogout consist of:

A A.Calcium pyrophosphate B B. Sodium urate C C. Potassium urate D D. Sodium pyrophosphate

15- Martel's sign is seen in which of the following conditions?

A A.Rheumatoid arthritis B B. Ankylosing spondylitis C C. Gout D D. Osteoarthritis

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